GBIO icon

Generation Bio

0.8800 USD
-0.0400
4.35%
At close Jan 14, 4:00 PM EST
Pre-market
0.9205
+0.0405
4.60%
1 day
-4.35%
5 days
-16.98%
1 month
-24.14%
3 months
-64.08%
6 months
-69.97%
Year to date
-20.72%
1 year
-51.11%
5 years
-96.44%
10 years
-96.44%
 

About: Generation Bio Co is a genetics medicine company that is focused on creating gene therapies to provide durable and redosable treatments for patients suffering from rare and untreated diseases. The company focuses on liver and retina-related diseases. It is developing two distinct and complementary platforms that It believes will enable highly differentiated therapeutic applications. Its first platform is a potent, highly selective ctLNP delivery system for nucleic acids, which is designed to avoid off-target clearance by the liver and spleen, enabling ctLNPs to persist in systemic circulation and allowing for highly selective and potent ligand-driven targeting to specific tissues and cell types. Its second platform is its novel iqDNA, which is an optimized variant of its ceDNA.

Employees: 174

0
Funds holding %
of 6,815 funds
Analysts bullish %

Fund manager confidence

Based on 2024 Q3 regulatory filings by fund managers ($100M+ AUM)

0% more funds holding in top 10

Funds holding in top 10: 1 [Q2] → 1 (+0) [Q3]

2.05% less ownership

Funds ownership: 85.06% [Q2] → 83.02% (-2.05%) [Q3]

3% less funds holding

Funds holding: 79 [Q2] → 77 (-2) [Q3]

14% less capital invested

Capital invested by funds: $160M [Q2] → $137M (-$22.8M) [Q3]

14% less first-time investments, than exits

New positions opened: 6 | Existing positions closed: 7

31% less repeat investments, than reductions

Existing positions increased: 20 | Existing positions reduced: 29

Research analyst outlook

1 Wall Street Analyst provided 1 year price targets over the past 3 months

Low target
$8
809%
upside
Avg. target
$8
809%
upside
High target
$8
809%
upside

1 analyst rating

positive
100%
neutral
0%
negative
0%
Needham
Gil Blum
23% 1-year accuracy
39 / 172 met price target
809%upside
$8
Buy
Maintained
8 Jan 2025

Financial journalist opinion

Neutral
GlobeNewsWire
1 week ago
Generation Bio to Apply ctLNP Delivery Technology to Develop siRNA Therapeutics for T Cell-Driven Autoimmune Diseases
CAMBRIDGE, Mass., Jan. 06, 2025 (GLOBE NEWSWIRE) -- Generation Bio Co. (Nasdaq:GBIO) a biotechnology company working to change what is possible for people living with T cell-driven autoimmune diseases, announced it is leveraging its validated T cell-directed lipid nanoparticle (ctLNP) to develop siRNA therapeutics to silence disease-driving targets in T cells. “We are excited to move Generation Bio toward the clinic by deploying our ctLNP to deliver siRNA to T cells. By precisely modulating T cell activity in vivo we believe we can address high-value, currently undruggable targets involved in the inflammation and tissue damage associated with T cell-driven autoimmune diseases,” said Geoff McDonough, M.D., chief executive officer of Generation Bio. “Our aim is to silence therapeutic T cell targets without impacting other immune cell types, unlocking a powerful new application for siRNA in the field. We plan to submit our first IND in the second half of 2026 and to enter the clinic within our cash runway, which is into the second half of 2027.”
Generation Bio to Apply ctLNP Delivery Technology to Develop siRNA Therapeutics for T Cell-Driven Autoimmune Diseases
Negative
Zacks Investment Research
2 months ago
Generation Bio Co. (GBIO) Reports Q3 Loss, Tops Revenue Estimates
Generation Bio Co. (GBIO) came out with a quarterly loss of $0.23 per share versus the Zacks Consensus Estimate of a loss of $0.28. This compares to loss of $0.43 per share a year ago.
Generation Bio Co. (GBIO) Reports Q3 Loss, Tops Revenue Estimates
Neutral
GlobeNewsWire
2 months ago
Generation Bio Announces the Presentation of Preclinical Data on ctLNP and iqDNA at the ESGCT 31st Annual Congress
CAMBRIDGE, Mass., Oct. 22, 2024 (GLOBE NEWSWIRE) -- Generation Bio Co. (Nasdaq:GBIO) a biotechnology company innovating genetic medicines for people living with rare and prevalent diseases, today presented data on its cell-targeted lipid nanoparticle (ctLNP) and immune-quiet DNA (iqDNA) platforms at the European Society of Gene and Cell Therapy (ESGCT) 31st Annual Congress.
Generation Bio Announces the Presentation of Preclinical Data on ctLNP and iqDNA at the ESGCT 31st Annual Congress
Neutral
GlobeNewsWire
4 months ago
Generation Bio to Present at the 2024 Cantor Global Healthcare Conference
CAMBRIDGE, Mass., Sept. 12, 2024 (GLOBE NEWSWIRE) -- Generation Bio Co. (Nasdaq:GBIO) a biotechnology company innovating genetic medicines for people living with rare and prevalent diseases, announced that Geoff McDonough, M.D., president and chief executive officer, will participate in a fireside chat at the 2024 Cantor Global Healthcare Conference on Thursday, September 19, 2024 at 10:20 a.m. ET in New York.
Generation Bio to Present at the 2024 Cantor Global Healthcare Conference
Negative
Zacks Investment Research
5 months ago
Generation Bio Co. (GBIO) Reports Q2 Loss, Tops Revenue Estimates
Generation Bio Co. (GBIO) came out with a quarterly loss of $0.31 per share versus the Zacks Consensus Estimate of a loss of $0.27. This compares to loss of $0.47 per share a year ago.
Generation Bio Co. (GBIO) Reports Q2 Loss, Tops Revenue Estimates
Neutral
GlobeNewsWire
5 months ago
Generation Bio to Present at the Canaccord Genuity 44th Annual Growth Conference
CAMBRIDGE, Mass., Aug. 06, 2024 (GLOBE NEWSWIRE) -- Generation Bio Co.  (Nasdaq:GBIO) a biotechnology company innovating genetic medicines for people living with rare and prevalent diseases, announced that Geoff McDonough, M.D., president and chief executive officer, will participate in a fireside chat at the Canaccord Genuity 44th Annual Growth Conference on Tuesday, August 13th, 2024 at 2:30 p.m. ET in Boston.
Generation Bio to Present at the Canaccord Genuity 44th Annual Growth Conference
Neutral
GlobeNewsWire
7 months ago
Generation Bio to Present at the 2024 TD Cowen Genetic Medicines & RNA Summit
CAMBRIDGE, Mass., June 14, 2024 (GLOBE NEWSWIRE) -- Generation Bio Co. (Nasdaq:GBIO) a biotechnology company innovating genetic medicines for people living with rare and prevalent diseases, announced that Geoff McDonough, M.D., president and chief executive officer, will participate in a fireside chat at the virtual 2024 TD Cowen Genetic Medicines & RNA Summit on Friday, June 21st, 2024 at 1:50 p.m. ET.
Generation Bio to Present at the 2024 TD Cowen Genetic Medicines & RNA Summit
Negative
Zacks Investment Research
8 months ago
Generation Bio Co. (GBIO) Reports Q1 Loss, Tops Revenue Estimates
Generation Bio Co. (GBIO) came out with a quarterly loss of $1.12 per share versus the Zacks Consensus Estimate of a loss of $0.36. This compares to loss of $0.53 per share a year ago.
Neutral
GlobeNewsWire
8 months ago
Generation Bio Announces Recent Business Highlights and First Quarter 2024 Financial Results
- Oral presentation at ASGCT described selective, high levels of therapeutic transgene delivery to T cells in vivo by cell-targeted lipid nanoparticle (ctLNP)
Generation Bio Announces Recent Business Highlights and First Quarter 2024 Financial Results
Neutral
GlobeNewsWire
8 months ago
Generation Bio Announces the Presentation of Preclinical Data on iqDNA and ctLNP Platforms at the ASGCT 27th Annual Meeting
CAMBRIDGE, Mass., May 09, 2024 (GLOBE NEWSWIRE) --   Generation Bio Co. (Nasdaq:GBIO) a biotechnology company innovating genetic medicines for people living with rare and prevalent diseases, today presented five posters on its immune-quiet DNA (iqDNA) and cell-targeted lipid nanoparticle (ctLNP) platforms as well as its enzymatic synthesis manufacturing at the American Society of Gene and Cell Therapy (ASGCT) 27th Annual Meeting. A sixth presentation on the company's ctLNP platform will be discussed in an oral presentation on Saturday, May 11.
Generation Bio Announces the Presentation of Preclinical Data on iqDNA and ctLNP Platforms at the ASGCT 27th Annual Meeting
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