CRISPR TherapeuticsCRSP
About: Crispr Therapeutics AG is a gene editing company focused on the development of Crispr/Cas9-based therapeutics. Crispr/Cas9 stands for clustered regularly interspaced short palindromic repeats (Crispr)/Crispr-associated protein 9 (Cas9), which is a revolutionary technology for precisely altering specific sequences of genomic DNA. The company is focused on using this technology to treat genetically defined diseases. Crispr's first approved drug is Casgevy, which was developed in collaboration with Vertex Pharmaceuticals and targets sickle-cell disease and transfusion-dependent beta-thalassemia, which have high unmet medical needs. The company is advancing a variety of gene editing programs in immuno-oncology, cardiovascular, and a stem cell-derived therapy to treat Type 1 diabetes.
Employees: 393
Fund manager confidence
Based on 2024 Q4 regulatory disclosures by fund managers ($100M+ AUM)
5.77% more ownership
Funds ownership: 69.81% [Q3] → 75.59% (+5.77%) [Q4]
6% less first-time investments, than exits
New positions opened: 65 | Existing positions closed: 69
6% less repeat investments, than reductions
Existing positions increased: 112 | Existing positions reduced: 119
3% less funds holding
Funds holding: 409 [Q3] → 396 (-13) [Q4]
9% less capital invested
Capital invested by funds: $2.79B [Q3] → $2.54B (-$251M) [Q4]
11% less call options, than puts
Call options by funds: $81.6M | Put options by funds: $91.6M
20% less funds holding in top 10
Funds holding in top 10: 5 [Q3] → 4 (-1) [Q4]
Research analyst outlook
12 Wall Street Analysts provided 1 year price targets over the past 3 months
12 analyst ratings
Needham Gil Blum 12% 1-year accuracy 19 / 157 met price target | 122%upside $84 | Buy Reiterated | 9 Apr 2025 |
Citigroup Yigal Nochomovitz 12% 1-year accuracy 5 / 41 met price target | 117%upside $82 | Buy Maintained | 18 Feb 2025 |
Morgan Stanley Terence Flynn 33% 1-year accuracy 7 / 21 met price target | 15%downside $32 | Underweight Maintained | 14 Feb 2025 |
Evercore ISI Group Liisa Bayko 40% 1-year accuracy 4 / 10 met price target | 162%upside $99 | Outperform Upgraded | 14 Feb 2025 |
Goldman Sachs Salveen Richter 11% 1-year accuracy 2 / 18 met price target | 51%upside $57 | Neutral Maintained | 13 Feb 2025 |
Financial journalist opinion
Based on 18 articles about CRSP published over the past 30 days









