LPTX icon

Leap Therapeutics

0.4001 USD
+0.0091
2.33%
At close Mar 14, 4:00 PM EDT
After hours
0.4127
+0.0126
3.15%
1 day
2.33%
5 days
-8.34%
1 month
-20.57%
3 months
-86.71%
6 months
-86.71%
Year to date
-87.57%
1 year
-81.81%
5 years
-96.92%
10 years
-99.49%
 

About: Leap Therapeutics Inc is in developing targeted antibody therapies for cancer treatment, focusing on inhibiting tumor-promoting pathways, targeting cancer-specific cell surface molecules, and activating the immune system against cancer cells. The company's lead program, DKN-01, targets Dickkopf-related protein 1 (DKK1) and is in clinical trials for esophagogastric, gynecologic, and colorectal cancers. Their second program, FL-301, targets Claudin18.2-expressing cells. Additionally, the company has two preclinical antibody programs, FL-302 and FL-501, aimed at developing transformative cancer treatments. Operating as a single segment, the company's sole focus is on developing innovative drugs to address unmet needs in cancer therapy. .

Employees: 54

0
Funds holding %
of 7,372 funds
Analysts bullish %

Fund manager confidence

Based on 2024 Q4 regulatory filings by fund managers ($100M+ AUM)

150% more first-time investments, than exits

New positions opened: 15 | Existing positions closed: 6

122% more repeat investments, than reductions

Existing positions increased: 20 | Existing positions reduced: 9

46% more capital invested

Capital invested by funds: $38.1M [Q3] → $55.6M (+$17.5M) [Q4]

19% more funds holding

Funds holding: 48 [Q3] → 57 (+9) [Q4]

11.72% more ownership

Funds ownership: 38.73% [Q3] → 50.46% (+11.72%) [Q4]

70% less call options, than puts

Call options by funds: $43K | Put options by funds: $142K

Research analyst outlook

We haven’t received any recent analyst ratings for LPTX.

Financial journalist opinion

Neutral
PRNewsWire
1 month ago
Leap Therapeutics Reports Initial Clinical Data from Part B of the DeFianCe Study and Part C of the DisTinGuish Study
35% objective response rate (ORR) in second-line colorectal cancer (CRC) patients treated with sirexatamab (DKN-01) plus bevacizumab and chemotherapy, compared to 23% ORR in the control arm DKK1 levels highly correlated with clinical activity in CRC population ORR benefit with sirexatamab observed across multiple potential Phase 3 CRC populations Preparations will begin for a registrational Phase 3 study in second-line CRC patients DisTinGuish Part C study in gastric cancer demonstrates activity in biomarker populations,  but not the signal necessary to advance into Phase 3 Leap to host a conference call to present clinical data today, January 28, 2025, at 8:00 a.m. ET CAMBRIDGE, Mass.
Leap Therapeutics Reports Initial Clinical Data from Part B of the DeFianCe Study and Part C of the DisTinGuish Study
Positive
Seeking Alpha
2 months ago
Leap Therapeutics: A Buy On Near-Term Data Catalysts In Stomach And Colon Cancer
Leap Therapeutics focuses on developing DKN-01, a promising monoclonal antibody for solid tumors, with encouraging early trial data in GI cancers. LPTX has a short operational runway with less than a year's worth of funds, making future funding a critical concern. Key phase 2 trial readouts for DKN-01 are expected in 2025, which could significantly impact the company's valuation and investment potential.
Leap Therapeutics: A Buy On Near-Term Data Catalysts In Stomach And Colon Cancer
Neutral
PRNewsWire
2 months ago
Leap Therapeutics to Participate at the 43rd Annual J.P. Morgan Healthcare Conference
CAMBRIDGE, Mass. , Jan. 6, 2025 /PRNewswire/ -- Leap Therapeutics, Inc. (Nasdaq:LPTX), a biotechnology company focused on developing targeted and immuno-oncology therapeutics, today announced that Douglas E.
Leap Therapeutics to Participate at the 43rd Annual J.P. Morgan Healthcare Conference
Neutral
PRNewsWire
3 months ago
Leap Therapeutics to Participate at Piper Sandler 36th Annual Healthcare Conference
CAMBRIDGE, Mass. , Nov. 26, 2024 /PRNewswire/ -- Leap Therapeutics, Inc. (Nasdaq:LPTX), a biotechnology company focused on developing targeted and immuno-oncology therapeutics, today announced that Douglas E.
Leap Therapeutics to Participate at Piper Sandler 36th Annual Healthcare Conference
Neutral
PRNewsWire
4 months ago
Leap Therapeutics Reports Third Quarter 2024 Financial Results
CAMBRIDGE, Mass. , Nov. 13, 2024 /PRNewswire/ -- Leap Therapeutics, Inc. (Nasdaq:LPTX), a biotechnology company focused on developing targeted and immuno-oncology therapeutics, today reported financial results for the third quarter ended September 30, 2024.
Leap Therapeutics Reports Third Quarter 2024 Financial Results
Neutral
PRNewsWire
5 months ago
Leap Therapeutics Announces Completion of Enrollment in Part B of the DeFianCe Study of DKN-01 for the Treatment of Colorectal Cancer Patients
CAMBRIDGE, Mass. , Sept. 30, 2024 /PRNewswire/ -- Leap Therapeutics, Inc. (Nasdaq: LPTX), a biotechnology company focused on developing targeted and immuno-oncology therapeutics, today announced that enrollment of 188 patients has been completed in the randomized controlled Part B of the DeFianCe study evaluating DKN-01, Leap's anti-Dickkopf-1 (DKK1) antibody, in combination with standard of care bevacizumab and chemotherapy as a second-line treatment for patients with advanced colorectal cancer (CRC).
Leap Therapeutics Announces Completion of Enrollment in Part B of the DeFianCe Study of DKN-01 for the Treatment of Colorectal Cancer Patients
Positive
24/7 Wall Street
6 months ago
3 Trending Biotech Penny Stocks
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3 Trending Biotech Penny Stocks
Neutral
PRNewsWire
7 months ago
Leap Therapeutics Reports Second Quarter 2024 Financial Results
CAMBRIDGE, Mass. , Aug. 12, 2024  /PRNewswire/ -- Leap Therapeutics, Inc. (Nasdaq:LPTX), a biotechnology company focused on developing targeted and immuno-oncology therapeutics, today reported financial results for the second quarter ended June 30, 2024.
Leap Therapeutics Reports Second Quarter 2024 Financial Results
Neutral
PRNewsWire
10 months ago
Leap Therapeutics Reports First Quarter 2024 Financial Results
CAMBRIDGE, Mass. , May 13, 2024 /PRNewswire/ -- Leap Therapeutics, Inc. (Nasdaq:LPTX), a biotechnology company focused on developing targeted and immuno-oncology therapeutics, today reported financial results for the first quarter ended March 31, 2024.
Leap Therapeutics Reports First Quarter 2024 Financial Results
Neutral
PRNewsWire
11 months ago
Leap Therapeutics Announces $40 Million Private Placement
Net proceeds, along with existing cash, cash equivalents, and marketable securities are expected to extend cash runway into Q2 2026 and enable expansion of DKN-01 DeFianCe clinical trial and development program CAMBRIDGE, Mass. , April 11, 2024 /PRNewswire/ -- Leap Therapeutics, Inc. (Nasdaq:LPTX), a biotechnology company focused on developing targeted and immuno-oncology therapeutics, today announced it has entered into a securities purchase agreement with a select group of institutional investors to issue and sell an aggregate of 12,660,993 shares of its common stock ("Common Stock") at a price of $2.82 per share and pre-funded warrants to purchase 1,523,404 shares of Common Stock at a price of $2.819 per share of Common Stock issuable upon exercise of the pre-funded warrants, in a private placement.
Leap Therapeutics Announces $40 Million Private Placement
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