PRLD icon

Prelude Therapeutics

1.30 USD
+0.41
46.40%
At close Dec 20, 4:00 PM EST
After hours
1.28
-0.02
1.54%
1 day
46.40%
5 days
63.19%
1 month
35.18%
3 months
-49.02%
6 months
-64.96%
Year to date
-68.06%
1 year
-67.25%
5 years
-95.04%
10 years
-95.04%
 

About: Prelude Therapeutics Incorp is a clinical-stage precision oncology company focused on discovering and developing small molecule therapies optimized to target the key driver mechanisms in cancers with high unmet needs. The company's pipeline includes four candidates currently in clinical development: PRT1419, a potent, selective inhibitor of MCL1; PRT2527, a potent and selective CDK9 inhibitor, PRT3645, a next-generation CDK4/6 inhibitor, and PRT3789 a first-in-class SMARCA2/BRM protein degrader.

Employees: 128

0
Funds holding %
of 6,809 funds
Analysts bullish %

Fund manager confidence

Based on 2024 Q3 regulatory filings by fund managers ($100M+ AUM)

113% more first-time investments, than exits

New positions opened: 17 | Existing positions closed: 8

15% more funds holding

Funds holding: 61 [Q2] → 70 (+9) [Q3]

3.5% more ownership

Funds ownership: 81.29% [Q2] → 84.79% (+3.5%) [Q3]

0% more call options, than puts

Call options by funds: $1K | Put options by funds: $1K

10% less repeat investments, than reductions

Existing positions increased: 19 | Existing positions reduced: 21

43% less capital invested

Capital invested by funds: $130M [Q2] → $74M (-$56.3M) [Q3]

Research analyst outlook

2 Wall Street Analysts provided 1 year price targets over the past 3 months

Low target
$4
208%
upside
Avg. target
$4.50
246%
upside
High target
$5
285%
upside

2 analyst ratings

positive
100%
neutral
0%
negative
0%
JMP Securities
Reni Benjamin
17% 1-year accuracy
6 / 36 met price target
208%upside
$4
Market Outperform
Reiterated
11 Dec 2024
HC Wainwright & Co.
Robert Burns
23% 1-year accuracy
36 / 155 met price target
285%upside
$5
Buy
Reiterated
8 Nov 2024

Financial journalist opinion

Based on 3 articles about PRLD published over the past 30 days

Neutral
GlobeNewsWire
1 week ago
Prelude Therapeutics Presents Preliminary Results of Phase 1 Dose-escalation Study of PRT2527 as Monotherapy and in Combination with Zanubrutinib in Patients with Relapsed/Refractory Lymphoid Malignancies
• PRT2527 demonstrated activity across a range of relapsed/refractory lymphoid malignancies, including patients who received prior CAR-T therapy
Prelude Therapeutics Presents Preliminary Results of Phase 1 Dose-escalation Study of PRT2527 as Monotherapy and in Combination with Zanubrutinib in Patients with Relapsed/Refractory Lymphoid Malignancies
Negative
Zacks Investment Research
3 weeks ago
After Plunging -31.47% in 4 Weeks, Here's Why the Trend Might Reverse for Prelude Therapeutics (PRLD)
Prelude Therapeutics (PRLD) is technically in oversold territory now, so the heavy selling pressure might have exhausted. This along with strong agreement among Wall Street analysts in raising earnings estimates could lead to a trend reversal for the stock.
After Plunging -31.47% in 4 Weeks, Here's Why the Trend Might Reverse for Prelude Therapeutics (PRLD)
Neutral
GlobeNewsWire
3 weeks ago
Prelude Therapeutics to Participate in Citizens JMP Securities Hematology and Oncology Summit
WILMINGTON, Del., Nov. 27, 2024 (GLOBE NEWSWIRE) -- Prelude Therapeutics Incorporated (Prelude) (Nasdaq: PRLD), a clinical-stage precision oncology company, announced today that the Company will participate in the Citizens JMP Securities Hematology and Oncology Summit, taking place virtually on December 2, 2024.
Prelude Therapeutics to Participate in Citizens JMP Securities Hematology and Oncology Summit
Positive
Zacks Investment Research
1 month ago
Down -39.13% in 4 Weeks, Here's Why You Should You Buy the Dip in Prelude Therapeutics (PRLD)
Prelude Therapeutics (PRLD) is technically in oversold territory now, so the heavy selling pressure might have exhausted. This along with strong agreement among Wall Street analysts in raising earnings estimates could lead to a trend reversal for the stock.
Down -39.13% in 4 Weeks, Here's Why You Should You Buy the Dip in Prelude Therapeutics (PRLD)
Neutral
GlobeNewsWire
1 month ago
Prelude Therapeutics Presents New Data from SMARCA Degrader Portfolio at the 36th EORTC-NCI-AACR Symposium
– Interim data from ongoing trial of PRT3789 showed additional clinical activity at higher doses in patients with non-small cell lung cancer (NSCLC)
Prelude Therapeutics Presents New Data from SMARCA Degrader Portfolio at the 36th EORTC-NCI-AACR Symposium
Neutral
GlobeNewsWire
2 months ago
Prelude Therapeutics Announces Publication of Abstracts for Presentation at the 36th EORTC-NCI-AACR Symposium
PRT3789, a novel, highly-selective SMARCA2 degrader in patients with advanced solid tumors with a SMARCA4 mutation plenary session presentation: October 24, 2024, 10:00 AM CEST (4:00 AM EST) PRT3789, a novel, highly-selective SMARCA2 degrader in patients with advanced solid tumors with a SMARCA4 mutation plenary session presentation: October 24, 2024, 10:00 AM CEST (4:00 AM EST)
Prelude Therapeutics Announces Publication of Abstracts for Presentation at the 36th EORTC-NCI-AACR Symposium
Neutral
GlobeNewsWire
3 months ago
Prelude Therapeutics' SMARCA2 Degrader PRT3789 Demonstrated Promising Initial Clinical Activity and Safety Profile in Phase 1 Trial
-  Encouraging signs of anti-tumor activity including objective responses observed in patients with SMARCA4-mutated non-small cell lung cancer (NSCLC) and esophageal cancer in early PRT3789 monotherapy dose escalation
Prelude Therapeutics' SMARCA2 Degrader PRT3789 Demonstrated Promising Initial Clinical Activity and Safety Profile in Phase 1 Trial
Neutral
GlobeNewsWire
3 months ago
Prelude Therapeutics Announces Publication of Abstract for Presentation at the European Society of Medical Oncology (ESMO) Congress 2024
PRT3789, a novel, highly-selective SMARCA2 degrader in patients with advanced solid tumors with a SMARCA4 mutation oral session presentation: September 13, 2024, 4:00 PM CEST (10:00 AM EST)
Prelude Therapeutics Announces Publication of Abstract for Presentation at the European Society of Medical Oncology (ESMO) Congress 2024
Neutral
GlobeNewsWire
4 months ago
Prelude Therapeutics Reports Second Quarter 2024 Financial Results and Provides Corporate Update
Interim Phase 1 data for its first-in-class, highly selective IV SMARCA2 degrader, PRT3789, selected for an oral presentation at the European Society for Medical Oncology (ESMO) Congress 2024 in September
Prelude Therapeutics Reports Second Quarter 2024 Financial Results and Provides Corporate Update
Neutral
GlobeNewsWire
5 months ago
Prelude Therapeutics Announces Clinical Collaboration with Merck to Evaluate PRT3789 in Combination with KEYTRUDA® (pembrolizumab) in Patients with SMARCA4-Mutated Cancers
Combining a first-in-class, highly selective SMARCA2 degrader with an anti-PD-1 therapy may potentially enhance the anti-tumor activity of either agent because of the complementary nature of the two mechanisms .
Prelude Therapeutics Announces Clinical Collaboration with Merck to Evaluate PRT3789 in Combination with KEYTRUDA® (pembrolizumab) in Patients with SMARCA4-Mutated Cancers
Charts implemented using Lightweight Charts™