Shattuck LabsSTTK
About: Shattuck Labs Inc is a biotechnology company specializing in the development of potential treatments for inflammatory and immune-mediated diseases. It is developing a potentially first-in-class antibody for the treatment of inflammatory bowel disease (IBD) and other inflammatory and immune-mediated diseases. The company's expertise in protein engineering and the development of novel tumor necrosis factor (TNF) receptor therapeutics comes together in its main program, SL-325, which has the potential to be a first-in-class death receptor 3 (DR3) antagonist antibody. In addition, the company is developing SL-425, a half-life extended version of SL-325, and multiple other preclinical DR3-based bispecific antibodies, for the treatment of patients with IBD.
Employees: 44
Fund manager confidence
Based on 2024 Q4 regulatory disclosures by fund managers ($100M+ AUM)
37% more repeat investments, than reductions
Existing positions increased: 26 | Existing positions reduced: 19
4% less funds holding
Funds holding: 78 [Q3] → 75 (-3) [Q4]
9.78% less ownership
Funds ownership: 76.04% [Q3] → 66.26% (-9.78%) [Q4]
19% less first-time investments, than exits
New positions opened: 13 | Existing positions closed: 16
50% less funds holding in top 10
Funds holding in top 10: 2 [Q3] → 1 (-1) [Q4]
69% less capital invested
Capital invested by funds: $125M [Q3] → $38.3M (-$86.5M) [Q4]
Research analyst outlook
1 Wall Street Analyst provided 1 year price targets over the past 3 months
1 analyst rating
Leerink Partners Faisal Khurshid 23% 1-year accuracy 3 / 13 met price target | 388%upside $4 | Outperform Initiated | 17 Mar 2025 |
Financial journalist opinion









